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clustering approach to Misophonia finds comorbidities

In a 2022 study, Norris attempted to characterize misophonia symptom presentation using cluster-based phenotyping by administering a comprehensive self-report survey indexing misophonia, tinnitus, sensory hypersensitivity, and psychiatric symptoms to 343 undergraduate students. Results indicated that individuals with misophonia showed elevated co-occurrence of tinnitus and broader sensory hypersensitivity across modalities. Misophonia was also associated with increased autism-like traits and schizotypal personality features, particularly in a subgroup with more complex symptom presentations. Additionally, higher rates of anxiety-related diagnoses were observed in the misophonia group, with anxiety partially accounting for heightened emotional reactivity to trigger sounds (Norris et al., 2022).