Body

In their 2019 fMRI study, Schröder and colleagues presented participants with trigger, neutral, and generally aversive sound clips and found condition-dependent differences in emotional responses between individuals with misophonia and controls. Compared to controls, misophonic participants reported greater anger, disgust, and depressive symptoms, with anger being particularly elevated. In the misophonia group, exposure to trigger sounds also elicited increased physiological arousal and greater activation in the right insula, right anterior cingulate cortex, and right superior temporal cortex, implicating the salience network in misophonia and supporting earlier findings by (Kumar et al., 2017).