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In a 2021 study using the MisoQuest to examine the comorbidity between misophonia, depression, and related clinical features among 94 psychiatric inpatients, Siepsiak and colleagues found that between 8.5% and 12.76% of patients with depression met criteria for misophonia, depending on whether mild cases were included. The MisoQuest demonstrated high diagnostic performance, with an accuracy of 92.55%, sensitivity of 66.67%, and specificity of 96.34%. Misophonia severity showed its strongest positive association with anxiety symptoms, and moderate positive correlations with depressive symptoms, PTSD-related intrusions and arousal, and somatic pain. Weaker positive correlations were observed with avoidance, vegetative symptoms, motor impulsivity, and non-planning impulsivity, while no significant relationships were found with attentional impulsivity or participant age. Overall, the results indicate that misophonia is relatively prevalent in depressed inpatient populations and is most strongly linked to anxiety, with broader but weaker associations across affective, somatic, and behavioral symptom domains.

trimmed to just talk about the quest

In a 2021 study using the MisoQuest to examine the comorbidity between misophonia, depression, and related clinical features among 94 psychiatric inpatients, Siepsiak and colleagues found that t he MisoQuest demonstrated high diagnostic performance, with an accuracy of 92.55%, sensitivity of 66.67%, and specificity of 96.34%. (Siepsiak et al., 2020)

trimmed to just talk about link to depression

trimmed to talk about anxiety

Siepsiak found that Misophonia severity strongly predicted anxiety symptoms (Siepsiak et al., 2020)

trimmed to PTSD

Siepsiak found that Misophonia severity strongly predicted PTSD symptoms (Siepsiak et al., 2020)